Sp2^tm1.1Htg
Targeted Allele Detail

Summary

• Symbol: Sp2^tm1.1Htg
• Name: Sp2 transcription factor; targeted mutation 1.1, H Troy Ghashghaei
• MGI ID: MGI:5471237
• Synonyms: Sp2^F
• Gene: Sp2 Location: Chr11:96844167-96873785 bp, - strand Genetic Position: Chr11, 60.17 cM, cytoband D
• Alliance: Sp2^tm1.1Htg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:194076
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked neo cassette with a 3' loxP site was inserted upstream of exon 3. An additional loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the neo cassette and left exons 3 and 4 floxed. (J:194076)

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sp2 Mutation: 151 strains or lines available

References

• Original: J:194076 Liang H, et al., Neural development is dependent on the function of specificity protein 2 in cell cycle progression. Development. 2013 Feb 1;140(3):552-61
• All: 2 reference(s)