Jdp2^tm1Aki
Targeted Allele Detail

Summary

• Symbol: Jdp2^tm1Aki
• Name: Jun dimerization protein 2; targeted mutation 1, Shizuo Akira
• MGI ID: MGI:5471474
• Gene: Jdp2 Location: Chr12:85645801-85686652 bp, + strand Genetic Position: Chr12, 39.74 cM, cytoband D3
• Alliance: Jdp2^tm1Aki page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:191061
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 3 kb fragment including exon2 and part of intron 2 was replaced with a neomycin resistance cassette. (J:191061)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Jdp2 Mutation: 14 strains or lines available

References

• Original: J:191061 Maruyama K, et al., The transcription factor jdp2 controls bone homeostasis and antibacterial immunity by regulating osteoclast and neutrophil differentiation. Immunity. 2012 Dec 14;37(6):1024-36
• All: 4 reference(s)