Zfp24^hmcns-2J
Spontaneous Allele Detail

Summary

• Symbol: Zfp24^hmcns-2J
• Name: zinc finger protein 24; hypomyelinated central nervous system 2 Jackson
• MGI ID: MGI:5472018
• Gene: Zfp24 Location: Chr18:24142759-24153867 bp, - strand Genetic Position: Chr18, 12.55 cM, cytoband B1
• Alliance: Zfp24^hmcns-2J page

Mutation origin

• Strain of Origin: BALB/cByJ

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: This spontaneous two base pair deletion in Chromosome 18 postitions 24,014,204 and 24,014,205 (GRCm38), which falls within exon 4, causes a frameshift that results in the substitution of 20 new amino acids in place of the last 18 amino acids of this 368 residue protein, thereby altering the last of four zinc finger domains. (J:202595)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Zfp24 Mutation: 23 strains or lines available

References

• Original: J:202595 Dionne L, et al., A spontaneous Zfp191 mouse mutation that alters 18 carboxyl terminal amino acids. MGI Direct Data Submission. 2013
• All: 1 reference(s)