Cited2^tm5Bha
Targeted Allele Detail

Summary

• Symbol: Cited2^tm5Bha
• Name: Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2; targeted mutation 5, Shoumo Bhattacharya
• MGI ID: MGI:5472021
• Synonyms: Cited2^MRG1
• Gene: Cited2 Location: Chr10:17598966-17601422 bp, + strand Genetic Position: Chr10, 7.18 cM, cytoband A2
• Alliance: Cited2^tm5Bha page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:192202
• Parent Cell Line: JM8.F6 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted
• Mutation: Insertion
• Mutation details: RMCE using Cited2^tm4Bha replaced the open reading frame with the rare human MRG1 mutation that lacks residues 158 through 214 (the SRJ region plus 18 flanking amino acids). (J:192202)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cited2 Mutation: 23 strains or lines available

References

• Original: J:192202 Chen CM, et al., Functional significance of SRJ domain mutations in CITED2. PLoS One. 2012;7(10):e46256
• All: 1 reference(s)