Rxfp2^{tm1c(EUCOMM)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Rxfp2^{tm1c(EUCOMM)Wtsi}
• Name: relaxin/insulin-like family peptide receptor 2; targeted mutation 1c, Wellcome Trust Sanger Institute
• MGI ID: MGI:5473310
• Synonyms: Rxfp2^f
• Gene: Rxfp2 Location: Chr5:149942140-150005649 bp, + strand Genetic Position: Chr5, 89.23 cM
• Alliance: Rxfp2^{tm1c(EUCOMM)Wtsi} page
• IMPC: Rxfp2 gene page

Mutation origin

• Mutant Cell Line: EPD0243_5_D11
• Germline Transmission: Earliest citation of germline transmission: J:194006
• Parent Cell Line: JM8.N4 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion Vector: L1L2_Bact_P
• Flp-mediated recombination removed the lacZ and expression cassette and left exon 4 floxed. (J:194006)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rxfp2 Mutation: 53 strains or lines available

References

• Original: J:194006 Huang Z, et al., Insulin-like 3 signaling is important for testicular descent but dispensable for spermatogenesis and germ cell survival in adult mice. Biol Reprod. 2012;87(6):143
• All: 1 reference(s)