Chtf18^tm1.2Khk
Targeted Allele Detail

Summary

• Symbol: Chtf18^tm1.2Khk
• Name: CTF18, chromosome transmission fidelity factor 18; targeted mutation 1.2, Klaus H Kaestner
• MGI ID: MGI:5473608
• Synonyms: Chtf18^flox
• Gene: Chtf18 Location: Chr17:25938004-25946409 bp, - strand Genetic Position: Chr17, 12.83 cM
• Alliance: Chtf18^tm1.2Khk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:194119
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT-flanked neo cassette with a 3' loxP site was inserted upstream of exon 7. An additional loxP site was inserted downsteam of exon 10. Flp-mediated recombination removed the neo cassette and left exons 7 through 10 floxed. (J:194119)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Chtf18 Mutation: 34 strains or lines available

References

• Original: J:194119 Berkowitz KM, et al., Disruption of CHTF18 causes defective meiotic recombination in male mice. PLoS Genet. 2012;8(11):e1002996
• All: 1 reference(s)