Cfl1^c5
Chemically induced Allele Detail

Summary

• Symbol: Cfl1^c5
• Name: cofilin 1, non-muscle; c5
• MGI ID: MGI:5473701
• Synonyms: C5
• Gene: Cfl1 Location: Chr19:5540483-5544059 bp, + strand Genetic Position: Chr19, 4.34 cM
• Alliance: Cfl1^c5 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU induced a T-to-A transversion leading to a p.F101I missense substitution. Western blot analysis of whole embryo lysates from homozygous mice indicates a decrease in protein expression. (J:98216, J:194042)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cfl1 Mutation: 25 strains or lines available

References

• Original: J:194042 Mahaffey JP, et al., Cofilin and Vangl2 cooperate in the initiation of planar cell polarity in the mouse embryo. Development. 2013 Mar;140(6):1262-71
• All: 3 reference(s)