Smarce1^tm1Tich
Targeted Allele Detail

Summary

• Symbol: Smarce1^tm1Tich
• Name: SWI/SNF related BAF chromatin remodeling complex subunit E1; targeted mutation 1, Tian Chi
• MGI ID: MGI:5474673
• Synonyms: BAF57^deltaR
• Gene: Smarce1 Location: Chr11:99099873-99121843 bp, - strand Genetic Position: Chr11, 62.92 cM, cytoband D
• Alliance: Smarce1^tm1Tich page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:194195
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

Allele Type: Targeted (Conditional ready, Null/knockout, Reporter) Mutations: Insertion, Insertion of gene trap vector Mutation details: An FRT flanked gene trap cassette (splice acceptor, neo, IRES, GFP and polyadenylation sequence) with a 3' loxP site was targeted downstream of exon 3. Western blot analysis confirmed the absence of protein expression in thymocytes. This knock-out allele is reversible following flp-mediated removal of the gene trap cassette. (J:194195)

Generation of the Smarce1^tm1Tich, Smarce1^tm2Tich and Smarce1^tm2.1Tich alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Smarce1 Mutation: 28 strains or lines available

References

• Original: J:194195 Chaiyachati BH, et al., LoxP-FRT Trap (LOFT): a simple and flexible system for conventional and reversible gene targeting. BMC Biol. 2013;10:96
• All: 2 reference(s)