Etv2^tm1Vkou
Targeted Allele Detail

Summary

• Symbol: Etv2^tm1Vkou
• Name: ets variant 2; targeted mutation 1, Valerie Kouskoff
• MGI ID: MGI:5474866
• Synonyms: Etv2^fl
• Gene: Etv2 Location: Chr7:30333041-30335277 bp, - strand Genetic Position: Chr7, 18.92 cM, cytoband A3
• Alliance: Etv2^tm1Vkou page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:194572
• Parent Cell Line: BK4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1. An FRT-flanked neo cassette with a 3'loxP site was inserted downstream of exon 7. (J:194572)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Etv2 Mutation: 14 strains or lines available

Notes

ES cell line = Ainv18, a tet-on inducible ES cell line made in BK4 ES cells.

References

• Original: J:194572 Wareing S, et al., The Flk1-Cre-mediated deletion of ETV2 defines its narrow temporal requirement during embryonic hematopoietic development. Stem Cells. 2012 Jul;30(7):1521-31
• All: 1 reference(s)