Ei24^tm1.1Hzha
Targeted Allele Detail

Summary

• Symbol: Ei24^tm1.1Hzha
• Name: etoposide induced 2.4 mRNA; targeted mutation 1.1, Hong Zhang
• MGI ID: MGI:5475024
• Gene: Ei24 Location: Chr9:36690449-36708630 bp, - strand Genetic Position: Chr9, 20.68 cM
• Alliance: Ei24^tm1.1Hzha page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:193420
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Cre-mediated recombination removed the floxed exon 3 and neo cassette. (J:193420)

Scheme for generating the Ei24^tm1Hzha and Ei24^tm1.1Hzha alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ei24 Mutation: 63 strains or lines available

References

• Original: J:193420 Zhao YG, et al., The p53-induced gene Ei24 is an essential component of the basal autophagy pathway. J Biol Chem. 2012 Dec 7;287(50):42053-63
• All: 1 reference(s)