Etv2^tm2.1Nshk
Targeted Allele Detail

Summary

• Symbol: Etv2^tm2.1Nshk
• Name: ets variant 2; targeted mutation 2.1, Shin-Ichi Nishikawa
• MGI ID: MGI:5475251
• Synonyms: Etv2fl
• Gene: Etv2 Location: Chr7:30333041-30335277 bp, - strand Genetic Position: Chr7, 18.92 cM, cytoband A3
• Alliance: Etv2^tm2.1Nshk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:193389
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted at nucleotide positions 23505 and 24318 of RP23-72M20 flanking the DNA binding domain and an FRT flanked neo cassette was inserted downstream of the first loxP site. Flp mediated recombination removed the neo cassette leaving the DNA binding domain floxed. (J:193389, J:214903)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Etv2 Mutation: 14 strains or lines available

References

• Original: J:193389 Ding G, et al., PDGF Receptor Alpha+ Mesoderm Contributes to Endothelial and Hematopoietic Cells in Mice. Dev Dyn. 2013 Mar;242(3):254-68
• All: 3 reference(s)