Bcl11a^tm1Peli
Targeted Allele Detail

Summary

• Symbol: Bcl11a^tm1Peli
• Name: BCL11 transcription factor A; targeted mutation 1, Pentao Liu
• MGI ID: MGI:5475335
• Synonyms: Bcl11a^eGFP
• Gene: Bcl11a Location: Chr11:24028056-24124123 bp, + strand Genetic Position: Chr11, 14.41 cM
• Alliance: Bcl11a^tm1Peli page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:194616
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Conditional ready, Reporter) Mutation: Insertion Mutation details: A loxP site was inserted upstream of exon 4. A reporter cassette (containing a loxP site, F3 site, IRES, EGFP, polyadenylation sequence, F3 and FRT site) was inserted downstream of the STOP codon in the 3'UTR. (J:194616)

Generation of the Bcl11a^tm1Peli allele

Expression

In Mice Carrying this Mutation:

41 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcl11a Mutation: 44 strains or lines available

References

• Original: J:194616 Yu Y, et al., Bcl11a is essential for lymphoid development and negatively regulates p53. J Exp Med. 2012 Dec 17;209(13):2467-83
• All: 2 reference(s)