Il33^tm1Amgn
Targeted Allele Detail

Summary

• Symbol: Il33^tm1Amgn
• Name: interleukin 33; targeted mutation 1, Amgen
• MGI ID: MGI:5476737
• Gene: Il33 Location: Chr19:29902514-29938118 bp, + strand Genetic Position: Chr19, 24.56 cM, cytoband C2
• Alliance: Il33^tm1Amgn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:185595
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT-flanked neomycin resistance cassette replaced the coding sequence. Flp-mediated recombination removed the selection cassette. (J:172073, J:192531)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il33 Mutation: 33 strains or lines available

References

• Original: J:185595 Ngoi SM, et al., Presensitizing with a Toll-like receptor 3 ligand impairs CD8 T-cell effector differentiation and IL-33 responsiveness. Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):10486-91
• All: 28 reference(s)