Tg(Scx-cre)HShuk
Transgene Detail

Summary

• Symbol: Tg(Scx-cre)HShuk
• Name: transgene insertion H, Chisa Shukunami
• MGI ID: MGI:5476830
• Synonyms: ScxCre-H
• Transgene: Tg(Scx-cre)HShuk Location: unknown
• Alliance: Tg(Scx-cre)HShuk page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F1

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Scx-cre)HShuk expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Scx (MGI:102934)

• Mutation details: A construct was generated with the cre recombinase sequence under control of approximately 11 kb of the Scx regulatory region (~4 kb of upstream sequence and ~5 kb of downstream sequence, retrieved from a bacterial artificial chromosome RP23-415D19). This construct was used to produce transgenic animals. Two lines were established with low transgene copy number (L) and high copy number (H). When lines were bred to reporter mice, cre activity was detected overlapping various Scx-positive expression domains including chondrogenic, tendonogenic and ligamentogenic regions, as well as in the lung, kidney and testes. (J:195053)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Scx (mouse) Summary of all recombinase alleles driven by Scx. Comparative matrix view of recombinase activities Alliance mouse Scx gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:195053 Sugimoto Y, et al., Generation and characterization of ScxCre transgenic mice. Genesis. 2013 Apr;51(4):275-83
• All: 3 reference(s)