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Rhbgtm1.1Idw
Targeted Allele Detail
Summary
Symbol: Rhbgtm1.1Idw
Name: Rhesus blood group-associated B glycoprotein; targeted mutation 1, I David Weiner
MGI ID: MGI:5477809
Synonyms: floxed Rhbg
Gene: Rhbg  Location: Chr3:88150181-88162016 bp, - strand  Genetic Position: Chr3, 38.78 cM
Alliance: Rhbgtm1.1Idw page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:195261
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 5 and a floxed neo cassette was inserted downstream of exon 9 via homologous recombination. The neo cassette was then deleted following electroporation of a supercoiled Neo expression plasmid into the ES cells. (J:195261)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rhbg Mutation:  22 strains or lines available
References
Original:  J:195261 Bishop JM, et al., Role of the Rhesus glycoprotein, Rh B glycoprotein, in renal ammonia excretion. Am J Physiol Renal Physiol. 2010 Nov;299(5):F1065-77
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory