Giptm1Nina
Targeted Allele Detail
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Symbol: |
Giptm1Nina |
Name: |
gastric inhibitory polypeptide; targeted mutation 1, Nobuya Inagaki |
MGI ID: |
MGI:5478539 |
Synonyms: |
GIP-GFP |
Gene: |
Gip Location: Chr11:95915371-95921657 bp, + strand Genetic Position: Chr11, 59.21 cM
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Alliance: |
Giptm1Nina page
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Germline Transmission: |
Earliest citation of germline transmission:
J:193877
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutation: |
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Insertion
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Mutation details: An EGFP and floxed neo cassette were inserted into exon 3. Immunohistochemistry confirmed EGFP expression and absence of endogenous protein expression in the small intestine.
(J:193877)
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Generation of the Giptm1Nina allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gip Mutation: |
13 strains or lines available
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Original: |
J:193877 Suzuki K, et al., Transcriptional regulatory factor X6 (Rfx6) increases gastric inhibitory polypeptide (GIP) expression in enteroendocrine K-cells and is involved in GIP hypersecretion in high fat diet-induced obesity. J Biol Chem. 2013 Jan 18;288(3):1929-38 |
All: |
11 reference(s) |
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