Cxcr3^tm1Arsa
Targeted Allele Detail

Summary

• Symbol: Cxcr3^tm1Arsa
• Name: C-X-C motif chemokine receptor 3; targeted mutation 1, Abhay R Satoskar
• MGI ID: MGI:5478545
• Synonyms: CIBER, Cxcr3^GFP
• Gene: Cxcr3 Location: ChrX:100775141-100777753 bp, - strand Genetic Position: ChrX, 44.58 cM
• Alliance: Cxcr3^tm1Arsa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:193492
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: An IRES, EGFP and floxed pgk-neo cassette were inserted in the 3' untranslated region of exon 2. Protein expression in activated T cells from mutant mice is similar to wild-type controls. Expression pattern of EGFP matches endogenous protein expression. (J:193492)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cxcr3 Mutation: 14 strains or lines available

References

• Original: J:193492 Oghumu S, et al., Distinct Populations of Innate CD8+ T Cells Revealed in a CXCR3 Reporter Mouse. J Immunol. 2013 Mar 1;190(5):2229-40
• All: 9 reference(s)