Kcnmb1^tm1Ltor
Targeted Allele Detail

Summary

• Symbol: Kcnmb1^tm1Ltor
• Name: potassium large conductance calcium-activated channel, subfamily M, beta member 1; targeted mutation 1, Ligia Toro
• MGI ID: MGI:5485152
• Synonyms: beta1^-
• Gene: Kcnmb1 Location: Chr11:33913013-33923641 bp, + strand Genetic Position: Chr11, 19.32 cM
• Alliance: Kcnmb1^tm1Ltor page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:195657
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 and 3 were deleted. The absence of transcript expression was confirmed in aorta, uterus and bladder. (J:195657)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kcnmb1 Mutation: 16 strains or lines available

References

• Original: J:195657 Li M, et al., The beta1-subunit of the MaxiK channel associates with the thromboxane A2 receptor and reduces thromboxane A2 functional effects. J Biol Chem. 2013 Feb 1;288(5):3668-77
• All: 1 reference(s)