Chst10^tm1Mifu
Targeted Allele Detail

Summary

• Symbol: Chst10^tm1Mifu
• Name: carbohydrate sulfotransferase 10; targeted mutation 1, Minoru Fukuda
• MGI ID: MGI:5485156
• Gene: Chst10 Location: Chr1:38902948-38937242 bp, - strand Genetic Position: Chr1, 17.24 cM
• Alliance: Chst10^tm1Mifu page

Enlarged uteri in Chst10^tm1Mifu/Chst10^tm1Mifu mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:195651
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: A neo cassette replaced the coding sequence in exon 5. Immunohistochemistry confirmed the absence of protein expression in the hippocampus. (J:195651)

Generation of the Chst10^tm1Mifu allele

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Chst10 Mutation: 22 strains or lines available

References

• Original: J:195651 Suzuki-Anekoji M, et al., In vivo regulation of steroid hormones by the Chst10 sulfotransferase in mouse. J Biol Chem. 2013 Feb 15;288(7):5007-16
• All: 2 reference(s)