Prkcz^tm1.1Msg
Targeted Allele Detail

Summary

• Symbol: Prkcz^tm1.1Msg
• Name: protein kinase C, zeta; targeted mutation 1.1, Robert O Messing
• MGI ID: MGI:5485241
• Gene: Prkcz Location: Chr4:155344586-155445818 bp, - strand Genetic Position: Chr4, 86.17 cM, cytoband E2
• Alliance: Prkcz^tm1.1Msg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:194398
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 9 was floxed and removed by cre-mediated recombination. Western blot analysis confirmed the absence of protein expression in the brain and kidney. (J:194398)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Prkcz Mutation: 43 strains or lines available

References

• Original: J:194398 Lee AM, et al., Prkcz null mice show normal learning and memory. Nature. 2013 Jan 17;493(7432):416-9
• All: 3 reference(s)