Id2^tm2.1Gtbz
Targeted Allele Detail

Summary

• Symbol: Id2^tm2.1Gtbz
• Name: inhibitor of DNA binding 2; targeted mutation 2.1, Gabrielle T Belz
• MGI ID: MGI:5486129
• Synonyms: Id2^fl
• Gene: Id2 Location: Chr12:25143798-25146091 bp, - strand Genetic Position: Chr12, 8.57 cM, cytoband B
• Alliance: Id2^tm2.1Gtbz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:194760
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1. An expression cassette (loxP site and FRT-flanked splice acceptor, IRES, EGFP and neo) was inserted into the 3' UTR. Flp-mediated recombination removed the splice acceptor, IRES, EGFP and neo. Exons 1 and 2 remain floxed. (J:194760)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Id2 Mutation: 21 strains or lines available

References

• Original: J:195908 Jackson JT, et al., Id2 expression delineates differential checkpoints in the genetic program of CD8alpha+ and CD103+ dendritic cell lineages. EMBO J. 2011 Jul 6;30(13):2690-704
• All: 9 reference(s)