Ube2q1^tm1Grz
Targeted Allele Detail

Summary

• Symbol: Ube2q1^tm1Grz
• Name: ubiquitin-conjugating enzyme E2Q family member 1; targeted mutation 1, Pawel Grzmil
• MGI ID: MGI:5486217
• Gene: Ube2q1 Location: Chr3:89680923-89691307 bp, + strand Genetic Position: Chr3, 39.19 cM, cytoband F2
• Alliance: Ube2q1^tm1Grz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:195898
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neo cassette replaced exons 5 and 6. Northern blot analysis confirmed the absence of transcript expression in the testis. (J:195898)

Expression

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ube2q1 Mutation: 16 strains or lines available

References

• Original: J:195898 Grzmil P, et al., Embryo implantation failure and other reproductive defects in Ube2q1-deficient female mice. Reproduction. 2013 Jan;145(1):45-56
• All: 1 reference(s)