Nox1^tm1.1Anrt
Targeted Allele Detail

Summary

• Symbol: Nox1^tm1.1Anrt
• Name: NADPH oxidase 1; targeted mutation 1.1, Asma Nusrat
• MGI ID: MGI:5486319
• Synonyms: Nox1^loxp
• Gene: Nox1 Location: ChrX:132987170-133038455 bp, - strand Genetic Position: ChrX, 55.69 cM
• Alliance: Nox1^tm1.1Anrt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:194294
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: A loxP site was inserted upstream of exon 13. An FRT-flanked neo cassette with a 3' loxP site and modified exon 13 with an insertion of an in-frame lacZ gene. The neo cassette was removed by FLP-mediated recombination and left exon 13 flanked by loxP sites. (J:194294)

Generation of the Nox1^tm1.1Anrt allele

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nox1 Mutation: 12 strains or lines available

References

• Original: J:194294 Leoni G, et al., Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair. J Clin Invest. 2013 Jan 2;123(1):443-54
• All: 2 reference(s)