Dpp4^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Dpp4^tm1Lex
• Name: dipeptidylpeptidase 4; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:5487468
• Gene: Dpp4 Location: Chr2:62160417-62242575 bp, - strand Genetic Position: Chr2, 35.85 cM, cytoband C2-D
• Alliance: Dpp4^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:195941
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• A lacZ/neo cassette replaced exon 1 and 2. (J:195941)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dpp4 Mutation: 73 strains or lines available

References

• Original: J:195941 Powell DR, et al., Improved glycemic control in mice lacking Sglt1 and Sglt2. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E117-30
• All: 1 reference(s)