Del(1Fmo4-Fmo2)1Eshe
Targeted Allele Detail

Summary

• Symbol: Del(1Fmo4-Fmo2)1Eshe
• Name: deletion, Chr 1, Elizabeth A Shephard 1
• MGI ID: MGI:5487815
• Synonyms: Del1Eshe, Del(Fmo4-Fmo2)1Eshe, Fmo1^-Fmo2^-Fmo4^-
• Gene: Del(1Fmo4-Fmo2)1Eshe Location: unknown Genetic Position: Chr1, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:196270
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intergenic deletion, Intragenic deletion
• Del(1Fmo4-Fmo2)1Eshe involves 4 genes/genome features (Fmo4, Fmo1, Gm32197 ...) View all
• Mutation details: Cre-mediated recombination between Fmo2^tm1Eshe and Fmo4^tm1Eshe removed exons 2 through 9 of Fmo2, the entire Fmo1 gene and exons 1 through 7 of Fmo4. (J:196270)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(1Fmo4-Fmo2)1Eshe Mutation: 0 strains or lines available

References

• Original: J:196270 Hernandez D, et al., Deletion of the mouse Fmo1 gene results in enhanced pharmacological behavioural responses to imipramine. Pharmacogenet Genomics. 2009 Apr;19(4):289-99
• All: 4 reference(s)