Myh9^tm1.2Gac
Targeted Allele Detail

Summary

• Symbol: Myh9^tm1.2Gac
• Name: myosin, heavy polypeptide 9, non-muscle; targeted mutation 1.2, Christian Gachet
• MGI ID: MGI:5489745
• Gene: Myh9 Location: Chr15:77644788-77726315 bp, - strand Genetic Position: Chr15, 36.81 cM
• Alliance: Myh9^tm1.2Gac page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:195436
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 1, and a floxed neo cassette was inserted downstream of exon 1. Cre-mediated recombination removed the neo cassette and exon 1. (J:195436)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myh9 Mutation: 219 strains or lines available

References

• Original: J:195436 Schachtner H, et al., Megakaryocytes assemble podosomes that degrade matrix and protrude through basement membrane. Blood. 2013 Mar 28;121(13):2542-52
• All: 1 reference(s)