Tg(CMV-TcrAHIII12.2)1Ecol
Transgene Detail

Summary

• Symbol: Tg(CMV-TcrAHIII12.2)1Ecol
• Name: transgene insertion 1, Edward J Collins
• MGI ID: MGI:5489794
• Transgene: Tg(CMV-TcrAHIII12.2)1Ecol Location: unknown
• Alliance: Tg(CMV-TcrAHIII12.2)1Ecol page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CMV-TcrAHIII12.2)1Ecol expresses 2 genes
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tcra (MGI:98553)
  mouse	Tcrb (MGI:98578)

• Mutation details: A cytomegalovirus (CMV) promoter drives expression of the T cell receptor alpha and beta chain genes (Tcra and Tcrb) from the AHIII 12.2 T cell clone, which originated in a C57BL/6 mouse (H2^b). This TCR recognizes the human self-peptide p1049 presented by the human HLA-A*0201 MHC molecule; it also recognizes the peptide p1058 (FAPGFFPYL) presented by the mouse MHC class I molecule H2-D^b. (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)