Sum2^M1Jus
Chemically induced Allele Detail

Summary

• Symbol: Sum2^M1Jus
• Name: suppressor of methyl CpG binding protein 2, 2; mutation 1, Monica J Justice
• MGI ID: MGI:5489913
• Synonyms: line 856
• Gene: Sum2 Location: Chr3:136077680-147596662 bp Genetic Position: Chr3, Syntenic
• Alliance: Sum2^M1Jus page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Undefined
• Mutation details: This allele was identified in a screen for attenuation of the Mecp2^tm1.1Bird/Y phenotype among male G1 offspring from crosses of 129S-Mecp2^tm1.1Bird/+ female mice by ENU-treated C57BL/6J males (G0). (J:198551)
• Inheritance: Other (see notes)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sum2 Mutation: 0 strains or lines available

Notes

Dominant modifier

References

• Original: J:198551 Buchovecky CM, et al., A suppressor screen in Mecp2 mutant mice implicates cholesterol metabolism in Rett Syndrome. Nat Genet. 2013;45(9):1013-20
• All: 1 reference(s)