Ntrk2^tm2.1Ddg
Targeted Allele Detail

Summary

• Symbol: Ntrk2^tm2.1Ddg
• Name: neurotrophic tyrosine kinase, receptor, type 2; targeted mutation 2.1, David D Ginty
• MGI ID: MGI:5490140
• Synonyms: TrkB^tauEGFP
• Gene: Ntrk2 Location: Chr13:58954383-59281784 bp, + strand Genetic Position: Chr13, 31.2 cM
• Alliance: Ntrk2^tm2.1Ddg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:196548
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A tau/EGFP fusion followed by an FRT-flanked neo cassette with a 3' loxP site replaced exon 2. Flp-mediated recombination removed the neo cassette. (J:196548)

Expression

In Mice Carrying this Mutation:

11 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ntrk2 Mutation: 66 strains or lines available

References

• Original: J:196548 Li L, et al., The functional organization of cutaneous low-threshold mechanosensory neurons. Cell. 2011 Dec 23;147(7):1615-27
• All: 13 reference(s)