Kcnq1^m1Anu
Chemically induced Allele Detail

Summary

• Symbol: Kcnq1^m1Anu
• Name: potassium voltage-gated channel, subfamily Q, member 1; mutation 1, Australian National University
• MGI ID: MGI:5490247
• Synonyms: ENU12/30a, Kcnq1^enu12
• Gene: Kcnq1 Location: Chr7:142660614-142980787 bp, + strand Genetic Position: Chr7, 88.12 cM
• Alliance: Kcnq1^m1Anu page

Mutation origin

• Strain of Origin: C57BL/6JAnu
• Project Collection: APF ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced an A to T substitution in exon 10 resulting in the amino acid substitution of a stop codon for lysine at position 435 (K435X). (J:196547)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Kcnq1 Mutation: 43 strains or lines available

References

• Original: J:196547 Liu X, et al., ENU mutagenesis screen to establish motor phenotypes in wild-type mice and modifiers of a pre-existing motor phenotype in tau mutant mice. J Biomed Biotechnol. 2011;2011:130947
• All: 1 reference(s)