Mpz^m1Anu
Chemically induced Allele Detail

Summary

• Symbol: Mpz^m1Anu
• Name: myelin protein zero; mutation 1, Australian National University
• MGI ID: MGI:5490251
• Synonyms: ENU16/069, Mpz^enu16
• Gene: Mpz Location: Chr1:170978282-170988699 bp, + strand Genetic Position: Chr1, 79.05 cM
• Alliance: Mpz^m1Anu page

Mutation origin

• Strain of Origin: BALB/c
• Project Collection: APF ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced an A to G substitution in exon 5 resulting in the amino acid substitution of glycine for aspartic acid at position 121 (D121G). Western blot analysis confirmed protein expression similar to wild-type mice. (J:196547)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mpz Mutation: 28 strains or lines available

References

• Original: J:196547 Liu X, et al., ENU mutagenesis screen to establish motor phenotypes in wild-type mice and modifiers of a pre-existing motor phenotype in tau mutant mice. J Biomed Biotechnol. 2011;2011:130947
• All: 1 reference(s)