Xpo4^{Gt(PT1-ATG)3EVal}
Gene trapped Allele Detail

Summary

• Symbol: Xpo4^{Gt(PT1-ATG)3EVal}
• Name: exportin 4; gene trap mutation 3E, Katherine A Vallis
• MGI ID: MGI:5490885
• Synonyms: 3E
• Gene: Xpo4 Location: Chr14:57814978-57902887 bp, - strand Genetic Position: Chr14, 30.11 cM, cytoband C2
• Alliance: Xpo4^{Gt(PT1-ATG)3EVal} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: The PT1-ATG gene trap vector has integrated into the endogenous gene 34 base pairs upstream of the ATG translation initiation site. This vector contains the engrailed 2 (En2) splice acceptor sequence joined to a promoterless lacZ (E. coli beta-galactosidase) reporter gene with an ATG translation initiation codon; it also contains the neomycin phosphotransferase gene under control of the phosphoglycerate kinase 1 (PGK1) promoter (PGK1-neo). (J:82809, J:197093)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Xpo4 Mutation: 85 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 2 reference(s)