Msrb1^tm1.1Rlev
Targeted Allele Detail

Summary

• Symbol: Msrb1^tm1.1Rlev
• Name: methionine sulfoxide reductase B1; targeted mutation 1.1, Rodney L Levine
• MGI ID: MGI:5490902
• Gene: Msrb1 Location: Chr17:24955616-24961752 bp, + strand Genetic Position: Chr17, 12.53 cM
• Alliance: Msrb1^tm1.1Rlev page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:196824
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 and 3 were floxed. Cre-mediated recombination removed exons 2 and 3. Western blot analysis confirmed the absence of protein expression. (J:196824)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Msrb1 Mutation: 8 strains or lines available

References

• Original: J:196824 Zhao H, et al., Methionine sulfoxide reductase contributes to meeting dietary methionine requirements. Arch Biochem Biophys. 2012 Jun 1;522(1):37-43
• All: 2 reference(s)