Hoxb2^tm3.2Fmr
Targeted Allele Detail

Summary

• Symbol: Hoxb2^tm3.2Fmr
• Name: homeobox B2; targeted mutation 3.2, Filippo M Rijli
• MGI ID: MGI:5490994
• Synonyms: Hoxb2^DeltaKO
• Gene: Hoxb2 Location: Chr11:96242458-96244846 bp, + strand Genetic Position: Chr11, 59.85 cM
• Alliance: Hoxb2^tm3.2Fmr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:197162
• Parent Cell Line: TBV2 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Hoxb2^tm3.1Fmr mice were mated to CMV-cre deleter animals to excise the floxed Hoxb2 region. (J:197162)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxb2 Mutation: 12 strains or lines available

References

• Original: J:197162 Di Bonito M, et al., Assembly of the auditory circuitry by a Hox genetic network in the mouse brainstem. PLoS Genet. 2013;9(2):e1003249
• All: 1 reference(s)