Tg(tetO-LMNB1)AF1Yfu
Transgene Detail

Summary

• Symbol: Tg(tetO-LMNB1)AF1Yfu
• Name: transgene insertion AF1, Ying-Hui Fu
• MGI ID: MGI:5491150
• Synonyms: Tg(tetO-Lmnb1)#Yfu, (TRE)-Lmnb1
• Transgene: Tg(tetO-LMNB1)AF1Yfu Location: unknown
• Alliance: Tg(tetO-LMNB1)AF1Yfu page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-LMNB1)AF1Yfu expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  LMNB1 (4001)

  Lmnb1

  (MGI:96795)

• Mutation details: The tetracyclin response element drives inducible expression of the FLAG tagged human cDNA. The founder line AF1 contains 1-2 copies of the transgene. (J:197168)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:197168 Heng MY, et al., Lamin B1 mediates cell-autonomous neuropathology in a leukodystrophy mouse model. J Clin Invest. 2013 Jun 3;123(6):2719-29
• All: 1 reference(s)