Gt(ROSA)26Sor^{tm1(Kdm6b)Scla}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(Kdm6b)Scla}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Stefano Casola
• MGI ID: MGI:5491321
• Synonyms: Rosa26^flSTOP-Jmjd3
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(Kdm6b)Scla} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:196346
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(Kdm6b)Scla} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Kdm6b (MGI:2448492)

• Mutation details: The targeting construct inserted into the locus contained a splice acceptor, floxed neo/STOP cassette, cDNA, FRT-flanked IRES-EGFP and a polyadenylation sequence. (J:196346)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:196346 Burgold T, et al., The H3K27 demethylase JMJD3 is required for maintenance of the embryonic respiratory neuronal network, neonatal breathing, and survival. Cell Rep. 2012 Nov 29;2(5):1244-58
• All: 1 reference(s)