Tg(Kdm6b*H1388A)21Gtes
Transgene Detail

Summary

• Symbol: Tg(Kdm6b*H1388A)21Gtes
• Name: transgene insertion 21, Giuseppe Testa
• MGI ID: MGI:5491325
• Synonyms: Jmjd3^mut21
• Transgene: Tg(Kdm6b*H1388A)21Gtes Location: unknown
• Alliance: Tg(Kdm6b*H1388A)21Gtes page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Kdm6b*H1388A)21Gtes expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Kdm6b (MGI:2448492)

• Mutation details: The transgene contains a BAC with a point mutation results in the amino acid substitution of alanine for histidine at position 1388 (H1388A). Lines 21 and 56 (with 6 and 3 copies of the transgene, respectively) were generated. (J:196346)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:196346 Burgold T, et al., The H3K27 demethylase JMJD3 is required for maintenance of the embryonic respiratory neuronal network, neonatal breathing, and survival. Cell Rep. 2012 Nov 29;2(5):1244-58
• All: 1 reference(s)