Cd244a^Chip
Chemically induced Allele Detail

Summary

• Symbol: Cd244a^Chip
• Name: CD244 molecule A; chip
• MGI ID: MGI:5491497
• Gene: Cd244a Location: Chr1:171386761-171412884 bp, + strand Genetic Position: Chr1, 79.52 cM
• Alliance: Cd244a^Chip page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a A>G point mutation which results in a threonine to alanine substitution (p.T342A) in the third immuno-receptor tyrosine-based switch motif (ITSM) in the encoded protein. (J:196519)
• Inheritance: Codominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd244a Mutation: 24 strains or lines available

Notes

Incidental mutations were detected in Cep170, GM1305 and Lbr with low to moderate predicted impact. J:196519

References

• Original: J:196519 Cashman S, et al., An ENU mutagenesis approach to dissect "self"-induced immune responses: Unraveling the genetic footprint of immunosurveillance. Oncoimmunology. 2012 Sep 1;1(6):856-862
• All: 1 reference(s)