Lcp2^m1Khoe
Chemically induced Allele Detail

Summary

• Symbol: Lcp2^m1Khoe
• Name: lymphocyte cytosolic protein 2; mutation 1, Kasper Hoebe
• MGI ID: MGI:5491498
• Synonyms: ace, Slp-76^ace
• Gene: Lcp2 Location: Chr11:33996928-34042281 bp, + strand Genetic Position: Chr11, 19.43 cM
• Alliance: Lcp2^m1Khoe page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a C to T point mutation that results in the amino acid substitution of isoleucine for threonine at position 428 (T428I). (J:229762)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lcp2 Mutation: 41 strains or lines available

References

• Original: J:196519 Cashman S, et al., An ENU mutagenesis approach to dissect "self"-induced immune responses: Unraveling the genetic footprint of immunosurveillance. Oncoimmunology. 2012 Sep 1;1(6):856-862
• All: 4 reference(s)