Smg6^{Tg(SMN1*delta5)1Pks}
Transgenic Allele Detail

Summary

• Symbol: Smg6^{Tg(SMN1*delta5)1Pks}
• Name: SMG6 nonsense mediated mRNA decay factor; transgene insertion 1, Nick Parkinson
• MGI ID: MGI:5493450
• Synonyms: SMNDelta5, Tg(SMN1*delta5-Smg6)1Pks
• Gene: Smg6 Location: Chr11:74816665-75055274 bp, + strand Genetic Position: Chr11, 45.76 cM
• Alliance: Smg6^{Tg(SMN1*delta5)1Pks} page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Smg6^{Tg(SMN1*delta5)1Pks} expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SMN1 (6606)

  Smn1	(MGI:109257)

• Mutation details: Mice with this transgenic insertion express a cDNA splice isoform of human SMN1 that lacks exon 5 under control of the ~750-bp SMN1 minimal promoter. The transgene is stably integrated as a single copy into intron 13 of the Smg6 locus. Expression of the transgene has been detected in all tissues analyzed. (J:169366)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 4 strains available Cell Lines: 0 lines available
• Carrying any Smg6 Mutation: 99 strains or lines available

References

• Original: J:169366 MouseBook^TM, Information obtained from MouseBook^TM, Medical Research Council Mammalian Genetics Unit, Harwell, UK. Unpublished. 2005-2013
• All: 1 reference(s)