Mapk8^tm1.1Jcbr
Targeted Allele Detail

Summary

• Symbol: Mapk8^tm1.1Jcbr
• Name: mitogen-activated protein kinase 8; targeted mutation 1.1, Jens C Bruning
• MGI ID: MGI:5494695
• Gene: Mapk8 Location: Chr14:33099855-33169115 bp, - strand Genetic Position: Chr14, 20.22 cM, cytoband B
• Alliance: Mapk8^tm1.1Jcbr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:195844
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed exon 2. (J:195844)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mapk8 Mutation: 74 strains or lines available

References

• Original: J:195844 Pal M, et al., Alteration of JNK-1 signaling in skeletal muscle fails to affect glucose homeostasis and obesity-associated insulin resistance in mice. PLoS One. 2013;8(1):e54247
• All: 1 reference(s)