Snai3^tm2.1Grid
Targeted Allele Detail

Summary

• Symbol: Snai3^tm2.1Grid
• Name: snail family zinc finger 3; targeted mutation 2.1, Tom Gridley
• MGI ID: MGI:5495409
• Synonyms: Snai3^null
• Gene: Snai3 Location: Chr8:123180947-123187472 bp, - strand Genetic Position: Chr8, 71.07 cM, cytoband E1
• Alliance: Snai3^tm2.1Grid page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:198115
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: An FRT-neo-FRT-loxP cassette was introduced to intron 1, and a second loxP site was place 5' of exon 1. Cre-mediated recombination removed exon 1 and the neo cassette. QRT-PCR confirmed the absence of transcript expression in embryos. (J:198115)

Construction of the Snai3^tm2.1Grid and Snai3^tm2.2Grid alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Snai3 Mutation: 17 strains or lines available

References

• Original: J:198115 Bradley CK, et al., The snail family gene snai3 is not essential for embryogenesis in mice. PLoS One. 2013;8(6):e65344
• All: 1 reference(s)