H2bc21^tm1Dlc
Targeted Allele Detail

Summary

• Symbol: H2bc21^tm1Dlc
• Name: H2B clustered histone 21; targeted mutation 1, Catherine Dulac
• MGI ID: MGI:5495670
• Gene: H2bc21 Location: Chr3:96128435-96131054 bp, + strand Genetic Position: Chr3, 41.67 cM, cytoband F1-F2
• Alliance: H2bc21^tm1Dlc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:197878
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An N-terminal fusion of the first 20 amino acids of Gap43 (for membrane localization) to mChrerry replaced the coding sequence. (J:197878)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any H2bc21 Mutation: 12 strains or lines available

References

• Original: J:197878 Santoro SW, et al., The activity-dependent histone variant H2BE modulates the life span of olfactory neurons. Elife. 2012;1:e00070
• All: 2 reference(s)