Ccbe1^tm1Mlkn
Targeted Allele Detail

Summary

• Symbol: Ccbe1^tm1Mlkn
• Name: collagen and calcium binding EGF domains 1; targeted mutation 1, Mark L Kahn
• MGI ID: MGI:5495674
• Synonyms: Ccbe1^LacZ
• Gene: Ccbe1 Location: Chr18:66189926-66424909 bp, - strand Genetic Position: Chr18, 39.13 cM, cytoband E1
• Alliance: Ccbe1^tm1Mlkn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:196696
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 3 was replaced with a gene trap cassette containing a splice acceptor, IRES-lacZ and an FRT flanked neo cassette vi homologous recombination. (J:196696)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccbe1 Mutation: 19 strains or lines available

References

• Original: J:196696 Zou Z, et al., The secreted lymphangiogenic factor CCBE1 is essential for fetal liver erythropoiesis. Blood. 2013 Apr 18;121(16):3228-36
• All: 3 reference(s)