Ccbe1^tm2.1Mlkn
Targeted Allele Detail

Summary

• Symbol: Ccbe1^tm2.1Mlkn
• Name: collagen and calcium binding EGF domains 1; targeted mutation 2.1, Mark L Kahn
• MGI ID: MGI:5495677
• Synonyms: Ccbe1^flox
• Gene: Ccbe1 Location: Chr18:66189926-66424909 bp, - strand Genetic Position: Chr18, 39.13 cM, cytoband E1
• Alliance: Ccbe1^tm2.1Mlkn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:196696
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT flanked neo cassette and loxP site were inserted upstream of exon 3 and a loxP site was inserted downstream of exon 3 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:196696)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccbe1 Mutation: 19 strains or lines available

References

• Original: J:196696 Zou Z, et al., The secreted lymphangiogenic factor CCBE1 is essential for fetal liver erythropoiesis. Blood. 2013 Apr 18;121(16):3228-36
• All: 3 reference(s)