Fabp6^tm1Lbal
Targeted Allele Detail

Summary

• Symbol: Fabp6^tm1Lbal
• Name: fatty acid binding protein 6; targeted mutation 1, Luis B Agellon
• MGI ID: MGI:5495685
• Gene: Fabp6 Location: Chr11:43486876-43492367 bp, - strand Genetic Position: Chr11, 25.81 cM
• Alliance: Fabp6^tm1Lbal page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:195544
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: A neomycin resistance cassette replaced introns 2 through 4. Western blot analysis confirmed the absence of protein expression in the small intestine. (J:195544)

Generation of the Fabp6^tm1Lbal allele

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fabp6 Mutation: 9 strains or lines available

References

• Original: J:195544 Praslickova D, et al., The ileal lipid binding protein is required for efficient absorption and transport of bile acids in the distal portion of the murine small intestine. PLoS One. 2012;7(12):e50810
• All: 2 reference(s)