Mycntm1.1Mlit
Targeted Allele Detail
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Symbol: |
Mycntm1.1Mlit |
Name: |
v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived; targeted mutation 1.1, Jian Fei |
MGI ID: |
MGI:5495991 |
Synonyms: |
NmycTRE |
Gene: |
Mycn Location: Chr12:12986094-12991837 bp, - strand Genetic Position: Chr12, 6.14 cM, cytoband A3-B
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Alliance: |
Mycntm1.1Mlit page
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Germline Transmission: |
Earliest citation of germline transmission:
J:196015
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Parent Cell Line: |
PRX-129S6 (ES Cell)
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Strain of Origin: |
129S6/SvEvTac
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Allele Type: |
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Targeted |
Mutation: |
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Insertion
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Mutation details: The targeting construct inserted tetracycline response element (TRE or tetO) and a loxP site into intron 1 and fused EGFP, FRT-flanked neomycin resistance cassette and an additional loxP site to the ATG translation initiation site in exon 2. Cre-mediated recombination removed EGFP and FRT-flanked neomycin resistance cassette.
(J:196015)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Mycn Mutation: |
25 strains or lines available
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Original: |
J:196015 Sun R, et al., Inducible and reversible regulation of endogenous gene in mouse. Nucleic Acids Res. 2012 Nov;40(21):e166 |
All: |
2 reference(s) |
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