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Tg(CAG-tTS)1Mlit
Transgene Detail
Summary
Symbol: Tg(CAG-tTS)1Mlit
Name: transgene insertion 1, Jian Fei
MGI ID: MGI:5496007
Synonyms: CAG-tTS
Transgene: Tg(CAG-tTS)1Mlit  Location: unknown  
Alliance: Tg(CAG-tTS)1Mlit page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe CAG promoter drives ubiquitous expression of the transcriptional repressor molecule (tetR) fused to the KRAB domain of human ZNF10 followed by a polyadenylation sequence. This transgene allows for inducible and reversable regulation of an endogenous gene containing the inserted tetracycline response element. Four lines were generated, including line tTS. (J:196015)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:196015 Sun R, et al., Inducible and reversible regulation of endogenous gene in mouse. Nucleic Acids Res. 2012 Nov;40(21):e166
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory