Pkd2^tm1Sia
Targeted Allele Detail

Summary

• Symbol: Pkd2^tm1Sia
• Name: polycystin 2, transient receptor potential cation channel; targeted mutation 1, Shinichi Aizawa
• MGI ID: MGI:5496378
• Gene: Pkd2 Location: Chr5:104607316-104653685 bp, + strand Genetic Position: Chr5, 50.68 cM
• Alliance: Pkd2^tm1Sia page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:195164
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Part of exon 1 was replaced with (5' to 3') lox71 site, lacZ gene with polyadenylation sequence, FRT-flanked neomycin resistance cassette, loxP site and polyadenylation sequence. (J:195164)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pkd2 Mutation: 85 strains or lines available

References

• Original: J:195164 Takao D, et al., Asymmetric distribution of dynamic calcium signals in the node of mouse embryo during left-right axis formation. Dev Biol. 2013 Apr 1;376(1):23-30
• All: 1 reference(s)