Tecpr1^tm1Chsa
Targeted Allele Detail

Summary

• Symbol: Tecpr1^tm1Chsa
• Name: tectonin beta-propeller repeat containing 1; targeted mutation 1, Chihiro Sasakawa
• MGI ID: MGI:5496539
• Gene: Tecpr1 Location: Chr5:144131260-144160433 bp, - strand Genetic Position: Chr5, 83.07 cM, cytoband G2
• Alliance: Tecpr1^tm1Chsa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:198333
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced exons 2 through 5. Western blot analysis confirmed the absence of protein expression in mouse embryonic fibroblasts. (J:198333)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Tecpr1 Mutation: 67 strains or lines available

References

• Original: J:198333 Ogawa M, et al., A Tecpr1-dependent selective autophagy pathway targets bacterial pathogens. Cell Host Microbe. 2011 May 19;9(5):376-89
• All: 1 reference(s)